Franklin County was formed in 1779 and, in the same year, the town of Louisburg was surveyed by William Christmas on land which had been purchased from Patewells & Jacobina Milner for that purpose. That deed from the Milners survives today in the first volume of county deeds. The county's first commissioners were William Brickell, William Green, William Hill, John Hunt, and Osborn Jeffreys and these men were charged with many tasks, the earliest of which were to build a courthouse and a jail. The first meeting of the men was the Franklin Court of Pleas and Quarter-Sessions of 1779 and it was held at the home of Benjamin Seawell. It is unfortunate that none of the records from those earliest days of Franklin county survive.

The first county courthouse was a log building erected circa 1781 either on or very near the current county courthouse location on Main Street between Court and Nash Streets. The log courthouse was replaced with a structure of brick and stone in 1849. The 1849 courthouse was completely remodeled in 1936 and again in 1968 when it was also enlarged.

The first jail was built close to the original courthouse and during the same timeframe, but it was destroyed by fire in 1872. It was replaced with a stone building which still stands, though now abandoned, on the south side of Nash Street about one-and-a-half blocks east of Main Street. The new Franklin County Jail & Sheriff's Department Complex was built in 1994 and is located west of downtown Louisburg on T. Kemp Road.